Question
GeneralGeneralGeneral

Isopropyl chloride undergoes hydrolysis by which mechanism?

Verified Answer

Isopropyl chloride (2-chloropropane) undergoes hydrolysis mainly by the SN1 (unimolecular nucleophilic substitution) mechanism under suitable conditions.

Explanation:

  • Isopropyl chloride is a secondary alkyl halide.
  • In polar protic solvents like water or alcohol, it tends to form a relatively stable secondary carbocation, favoring the SN1 mechanism.

SN1 Mechanism Steps:

  1. Formation of Carbocation (Slow Step):
    The C–Cl bond breaks to form a secondary carbocation:
    (CH₃)₂CHCl → (CH₃)₂CH⁺ + Cl⁻
  2. Nucleophilic Attack (Fast Step):
    Water (acting as a nucleophile) attacks the carbocation:
    (CH₃)₂CH⁺ + H₂O → (CH₃)₂CHOH₂⁺
  3. Deprotonation:
    The intermediate loses a proton to form alcohol:
    (CH₃)₂CHOH₂⁺ → (CH₃)₂CHOH + H⁺

Final Product:
Isopropyl alcohol (propan-2-ol)

Important Notes:

  • SN1 is favored in polar protic solvents
  • Reaction rate depends only on the concentration of the substrate
  • Carbocation stability plays a key role

Conclusion:
Isopropyl chloride typically undergoes hydrolysis via the SN1 mechanism, forming isopropyl alcohol as the final product.