Proper hygiene, especially handwashing, is effective against 'foe' microorganisms because it physically removes or significantly reduces their numbers from surfaces like skin. Many pathogenic microorganisms are transmitted through direct contact or by touching contaminated surfaces and then touching one's face. Handwashing with soap and water dislodges and washes away these microbes, preventing their entry into the body and thus breaking the chain of infection. It's a simple yet powerful barrier against disease transmission.